Heroin-Induced Leukoencephalopathy
نویسندگان
چکیده
منابع مشابه
Heroin-induced spongiform leukoencephalopathy: value of diffusion MR imaging.
The diffusion-weighted (DW) magnetic resonance (MR) imaging findings of a patient with subacute stage of heroin-induced vacuolating myelinopathy are reported. The diffuse decrease of apparent diffusion coefficient (ADC) of the white matter on DW imaging is attributed to restricted water diffusion, which is known to be caused by fluid entrapment within the myelin lamellae without demyelination.
متن کاملMicrovascular Damage Is Involved in the Pathogenesis of Heroin Induced Spongiform Leukoencephalopathy
OBJECTIVE To investigate whether microvascular damage is involved in the pathogenesis of heroin induced spongiform leukoencephalopathy (HSLE). METHODS The brain tissues were collected from 4 HSLE patients and 5 controls and then fixed in 4% paraformaldehyde. The frontal lobe, corpus callosum and cerebellum were separated. The expressions of myelin base protein (MBP) and CD34 were detected by ...
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Retrospective MR studies of four patients with neurologic symptoms after inhalation of contaminated heroin vapor revealed extensive, typically symmetrical lesions in the white matter of the cerebrum, cerebellum, and midbrain. Selective involvement of the corticospinal tract, the solitary tract, and the lemniscus medialis also has been found.
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Parkinson 's dis ease is a slowl y progressive, neurodegenerative di sorder a ffec t ing one in 1,000 of th e gen eral population ; its in cid e nce increases with age , but the ca use remains unknown . The di sease is characte r ized pathologically by a loss of neurons fr om th e pigmented subs ta n t ia nigra par s co mpacta , and a tr iad of ph ysical symptoms of rigidity, tremor, and bradyk...
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An association between leukoencephalopathy, a disease of the white matter of the brain, and smoking heroin is well recognized. This paper describes 27 cases of leukoencephalopathy identified in two cities in British Columbia, Canada 2001-2006; the largest number of geographically and temporally defined reported cases in North America.Twenty cases of leukoencephalopathy were identified in and ar...
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ژورنال
عنوان ژورنال: Cureus
سال: 2021
ISSN: 2168-8184
DOI: 10.7759/cureus.13093